C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/272
C07D 461/00 (2006.01)
Patent
CA 1199638
Eburnane-oxime ethers, process for their preparation and pharma- ceutical compositions thereof ABSTRACT The invention relates to optically active or racemic eburnane-oxime ethers of the formulae (Ia) and/or (Ib) Image (Ia) Image (Ib) wherein R represents an alkyl group having 1 or 2 carbon atoms, R2 represents an alkyl group having 1 to 6 carbon atoms, and the configuration of the hydrogen in the 3-position and the R2 group is .alpha.,.alpha. and/or .beta.,.beta. or .alpha.,.beta. and/or .beta.,.alpha. and acid addition salts thereof. The new compounds show valuable pharmaceutical activ- ities, thus, are potent CNS-tranquillants, smooth muscle relax- ants, sedatives and hypnotic agents, and can therefore be employed as active ingredients of pharmaceutical compositions, which are also within the scope of the present invention.
431473
Balazs Maria
Ezer Elemer
Kalaus Gyorgy
Karpati Egon
Kiss Bela
Fetherstonhaugh & Co.
Richter Gedeon Vegyeszeti Gyar Rt
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