C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/705 (2006.01) A01N 63/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/72 (2006.01) C12Q 1/68 (2006.01) G06F 3/13 (2006.01) G06F 15/00 (2006.01)
Patent
CA 2527179
The present invention relates to structural studies of the functional insect ecdysone receptor. More particularly, the invention relates to the crystal structure of the whitefly ecdysone receptor ligand-binding domain, specifically that of Bemisia tabaci, and uses of the crystal and related structural information to select and screen for compounds that interact with the receptor.
La présente invention concerne des études structurelles du récepteur d'ecdysone d'un insecte fonctionnel. Elle concerne plus particulièrement la structure crystalline du domaine de liaison de ligands d'un récepteur d'ecdysone des Leyrodidae, et notamment des Bemisia tabaci, et l'utilisation des informations sur les structures cristallines et d'autres informations structurelles correspondantes pour sélectionner et cribler les composés qui intéragissent avec le récepteur.
Carmichael Jennifer A.
Epa Vidana C.
Graham Lloyd
Hannan Garry N.
Hill Ronald J.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Commonwealth Scientific And Industrial Research Organisation
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