Ed-b fibronectin as stratification marker for anti-tumor drugs

Details Ed-b fibronectin as stratification marker for anti-tumor drugs Ed-b fibronectin as stratification marker for anti-tumor drugs

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) C12N 5/09 (2010.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2698616

The present invention relates to a method for stratifying tumor cells comprising the steps:(a) providing a sample comprising tumor cells to be analysed, (b) contacting said sample with an ED-B fibronectin-specific molecule and assessing the binding thereof to tumor cells in said sample, and (c) stratifying said tumor cells based on the assessment of step (b).

La présente invention concerne un procédé permettant de stratifier des cellules tumorales consistant : (a) à se procurer un échantillon comportant des cellules tumorales devant être analysées, (b) à mettre en contact ledit échantillon avec une molécule spécifique de la fibronectine ED-B et à évaluer la liaison de celle-ci aux cellules tumorales dans ledit échantillon, et (c) à stratifier lesdites cellules tumorales sur la base de l'évaluation de l'étape (b).

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