Edrophonium-atropine composition and therapeutic uses thereof

A - Human Necessities – 61 – K

Patent

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167/230

A61K 31/46 (2006.01)

Patent

CA 1200500

Abstract of the Disclosure A composition is provided which includes a balanced combination of an edrophonium component and an atropine component. A preferred embodiment has 0.5 mg of edrophonium chloride and 8 micrograms of atropine sulfate, with respect to patient weight. The inventive composition is useful to antagonize nondepolarizing blockade during medical treatment when muscle relaxation is no longer necessary, provides extremely rapid onset of action and results in minimal heart rate changes.

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