Educational kit and method using tumor necrosis...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2393527

An educational kit containing Ztsg1 gene and optionally, a Ztsg1 polypeptide, antibody, and anti-idiotypic antibody. Tumor necrosis factor-stimulated protein (Ztsg1), polynucleotides that encode it and antibodies, which bind to it. Ztsg1 can be administered to an individual to stimulate the immune system. Antibodies to Ztsg1 can be used to diagnose rheumatoid arthritis in an individual.

L'invention concerne une trousse pédagogique contenant le gène Ztsg1 et éventuellement, un polypeptide, un anticorps et un anticorps anti-idiotype Ztsg1. L'invention concerne également une protéine stimulée par le facteur de nécrose tumorale (Ztsg1), des polynucléotides codant pour cette protéine et des anticorps qui se lient à cette protéine. Ztsg1 peut être administrée à une personne afin de stimuler son système immunitaire. Des anticorps dirigés contre Ztsg1 peuvent être utilisés afin de diagnostiquer la polyarthrite rhumatoïde chez une personne.

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