Effectors of par-2 activation and their use in the...

Details Effectors of par-2 activation and their use in the... Effectors of par-2 activation and their use in the...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 37/00 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2733041

The present invention relates to the recognition that PAR-2 receptors amplify the inflammatory response and that effectors of PAR-2 activation can thus be used to modulate the inflammatory response and thereby impart therapeutic benefit to patients. The invention is particularly directed to the use of PAR-2 effectors in the treatment of inflammation and nociception (pain) caused by inflammation, cancer and injury. The invention is particularly directed to negative effectors of PAR-2 activation, and more particularly to anti-PAR-2 antibodies that are negative effectors of PAR-2 activation.

La présente invention porte sur la reconnaissance du fait que des récepteurs PAR-2 amplifient la réponse inflammatoire et du fait que des effecteurs de l'activation PAR-2 peuvent ainsi être utilisés pour moduler la réponse inflammatoire et ainsi conférer un avantage thérapeutique à des patients. L'invention porte en particulier sur l'utilisation d'effecteurs PAR-2 dans le traitement d'une inflammation et d'une nociception (douleur) provoquée par une inflammation, un cancer et une lésion. L'invention porte en particulier sur des effecteurs négatifs de l'activation PAR-2, et de façon plus particulière sur des anticorps anti-PAR-2 qui sont des effecteurs négatifs de l'activation PAR-2.

Affiliated with

Also associated with

Rating

Effectors of par-2 activation and their use in the... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Effectors of par-2 activation and their use in the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Effectors of par-2 activation and their use in the... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2050975