Effects of glucagon-like peptide-1 (7-36) on...

A - Human Necessities – 61 – K

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A61K 38/26 (2006.01) A61P 1/00 (2006.01) A61P 1/12 (2006.01) A61P 25/30 (2006.01) A61P 41/00 (2006.01) A61K 38/12 (2006.01)

Patent

CA 2402733

The present invention provides an effective method for inhibiting antro- duodenal motility in healthy subjects and patients suffering from various disorders, without the side effects associated with other pharmaceutical compositions. GLP-1 slows antro-duodenal motility and may be used for the treatment or prevention of gastrointestinal disorders such as diarrhea, postoperative dumping syndrome and irritable bowel syndrome, and also premedication in endoscopic procedures.

La présente invention concerne une méthode efficace d'inhibition de la motilité antro-duodénale chez des sujets en bonne santé et des patients souffrant de divers troubles, sans occasionner d'effets secondaires associés à d'autres compositions pharmaceutiques. GLP-1 ralentit la motilité antro-duodénale et peut être utilisé dans le traitement ou la prévention de troubles gastro-intestinaux, tels que la diarrhée, le syndrome de l'anse efférente postopératoire et le syndrome du côlon irritable, et également dans la prémédication des interventions endoscopiques.

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