Effects of sporoderm-broken germination activated ganoderma...

Details Effects of sporoderm-broken germination activated ganoderma... Effects of sporoderm-broken germination activated ganoderma...

A - Human Necessities

61

K

A61K 36/074 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2534374

The present invention provides a method for treating patients with spinal cord injury by administering germination activated Ganoderma lucidium spores (GASP) to the patients. The GASP are sporoderm-broken. The GASP promote axon regeneration and improve motor neuron survival in the injured spinal cord. The present invention also provides a method for promoting proliferation and/or differentiation of neural stem cells in a mammal, which comprises orally administering sporoderm-broken germination activated Ganoderma lucidum spores (GASP) to the mammal. The effects of GASP on proliferation and/or differentiation of neural stem cells are particularly prominent in mammals after a spinal cord injury.

L'invention concerne une méthode de traitement de patients souffrant de lésions de la moelle épinière par administration aux patients de spores de Ganoderma lucidium à germination activée (GASP). Le sporoderme des spores de GASP est rompu. Les spores de GASP promeuvent la régénération des axones et améliorent la survie des motoneurones dans la moelle épinière blessée. L'invention concerne également une méthode pour promouvoir la prolifération et/ou la différentiation des cellules souches nerveuses chez un mammifère ; selon cette méthode, on administre par voie orale au mammifère des spores de Ganoderma lucidum à germination activée (GASP) et à sporoderme rompu. Les effets des spores de GASP sur la prolifération et/ou la différentiation ces cellules souches nerveuses est particulièrement important chez des mammifères après une lésion de la moelle épinière.

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