Effervescent formulations

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/46 (2006.01) A61K 9/00 (2006.01) A61K 31/137 (2006.01) A61K 31/355 (2006.01) A61K 31/43 (2006.01) A61K 31/515 (2006.01) A61K 31/5513 (2006.01) A61K 31/7048 (2006.01)

Patent

CA 2326502

The invention relates to rapidly decomposing forms of administering alkali- sensitive active agents, more particularly selegiline, for oral applications in the form of fizzy formulations, containing an alkali- sensitive active agent and a fizzy base consisting of one or several alkaline earth carbonates, an organically edible acid and/or alkali salt of a citric acid and optionally pharmaceutically usable additives.

L'invention concerne des formes de préparation d'agents actifs sensibles au milieu alcalin, notamment de sélégiline. Ces formes de préparation de décomposition rapide et destinées à une administration orale se présentent sous la forme de formulations de spray contenant un agent actif sensible au milieu alcalin et une base de spray composée, à son tour, d'au moins un carbonate alcalino-terreux, d'un acide comestible organique et/ou d'un sel alcalin d'acide citrique et éventuellement d'agents actifs pharmaceutiquement utilisables.

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