Effervescent ibuprofen formulation with high dissolution...

Details Effervescent ibuprofen formulation with high dissolution... Effervescent ibuprofen formulation with high dissolution...

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 31/19 (2006.01)

Patent

CA 2664420

The invention relates to ibuprofen effervescent preparations that comprise (a) an active ingredient-containing granulate that contains a water-soluble ibuprofen salt and a basic auxiliary agent, and (b) an effervescent granulate that contains an acidic component and a component producing carbon dioxide. The invention also relates to methods for the production thereof.

L'invention concerne des préparations effervescentes à l'ibuprofène comprenant : (a) des granulés contenant le principe actif, à savoir un sel d'ibuprofène hydrosoluble, et un adjuvant basique, et (b) des granulés effervescents qui contiennent un composant acide et un composant générant du dioxyde de carbone. Cette invention se rapporte en outre à des procédés de production correspondants.

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