A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 36/73 (2006.01) A61K 36/185 (2006.01) A61K 36/45 (2006.01) A61P 29/00 (2006.01) A61P 31/12 (2006.01) C12S 3/00 (2006.01)
Patent
CA 2506651
This invention provides a process for the preparation of compositions enriched in total phenols from a crude plant extract. The process includes a novel column purification step using a brominated polystyrene resin. This invention also includes compositions enriched in total phenols. The enriched compositions are characterized as containing monomeric, oligomeric and polymeric phenols and having HPLC chromatograms substantially as set forth in Figures 10-13. This invention encompasses methods of using the total phenol- enriched compositions for treating warm-blooded animals, including humans, infected with paramyxovaridae such as respiratory syncytial virus, orthomyoxovaridae such as influenza A, B, and C, parainfluenza, Herpes viruses such as HSV-1 and HSV-2, and Flaviviruses such as West Nile Virus, and for treating inflammation such as caused by arthritis, stress and digestive disease.
Cette invention porte sur un procédé de préparation de compositions enrichies en phénols totaux à partir d'un extrait brut de plante. Le procédé comprend une nouvelle étape de purification sur colonne utilisant une résine de polystyrène bromée. Cette invention comprend également des compositions enrichies en phénols totaux. Les compositions enrichies sont caractérisées en ce qu'elles contiennent des phénols monomères, oligomères et polymères et possèdent des chromatogrammes HPLC tel qu'indiqué dans les figures 10 à13. Cette invention porte également sur des procédés d'utilisation des compositions enrichies en phénols totaux et visant à traiter des animaux à sang chaud tels que les humains, et infectés par des paramyxovaridae tels que le virus syncytial respiratoire, des orthomyoxovaridae tels que la grippe A, B et C, le virus parainfluenza, les virus de l'herpès tels que le HSV-1 et le HSV-2, et les flavivirus tels que le virus du Nil occidental, et traiter des inflammations telles que l'arthrite, le stress et les troubles digestifs.
Bailey David T.
Daugherty F. Joseph
Freeberg Delano R.
Gourdin Gerald T.
Nichols Rebecca L.
Gowling Lafleur Henderson Llp
Phenolics Llc
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