C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 473/16 (2006.01) A61K 31/52 (2006.01) A61P 19/02 (2006.01) A61P 35/00 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2760794
The present invention relates to novel pyrimidine, pyrrolo-pyrimidine, pyrrolo-pyridine, pyridine, purine and triazine compounds which are able to modulate epidermal growth factor receptor (EGFR), including Her-kinases, and the use of such compounds in the treatment of various diseases, disorders or conditions.
La présente invention porte sur de nouveaux composés pyrimidine, pyrrolo-pyrimidine, pyrrolo-pyridine, pyridine, purine et triazine qui sont capables de moduler le récepteur du facteur de croissance épidermique (EGFR), comprenant les Her-kinases, et sur l'utilisation de tels composés dans le traitement de diverses maladies, divers troubles ou divers états.
Eck Michael J.
Gray Nathanael S.
Janne Pasi
Zhou Wenjun
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Dana Farber Cancer Institute
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