Egfr inhibitors promote axon regeneration

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/705 (2006.01) C07K 14/485 (2006.01)

Patent

CA 2610830

Compositions and methods for promoting neural regeneration in a patient determined to have a lesion in a mature CNS neuron are disclosed. The method comprises the step of contacting the neuron with an EGFR inhibitor sufficient to promote regeneration of the neuron.

L'invention concerne des compositions et des méthodes d'activation d'une régénération neurale chez un patient présentant une lésion dans une neurone mature du SNC. La méthode consiste à placer la neurone au contact d'un inhibiteur EGFR pouvant activer la régénération de la neurone.

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