Ehv-1 vectors

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/86 (2006.01) C12N 7/01 (2006.01) C12N 15/869 (2006.01)

Patent

CA 2275546

The invention relates to manipulation of equine herpes virus for use in gene therapy and in particular to modifications of the virus so that it can carry heterologous material and furthermore, preferably, be replication deficient so that the virus cannot replicate in the target tissue.

L'invention concerne la manipulation d'un virus herpétique équin destiné à être utilisé dans une thérapie génique; l'invention concerne en particulier la modification du virus de sorte qu'il puisse servir de support à une matière hétérologue et qu'il présente ensuite de préférence une déficience de réplication afin de ne pas pouvoir se répliquer dans le tissu cible.

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