Elastase inhibitor

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 5/078 (2006.01) A61K 31/40 (2006.01) A61K 38/55 (2006.01) C07D 207/16 (2006.01) C07K 5/062 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2130279

ABSTRACT OF THE DISCLOSURE A compound of general formula [I]: Image [I] or its hydrates wherein R represents hydrogen atom, a lower alkanoyl amino group, a lower alkyloxy carbonylamino group or an aralkyloxy carbonylamino group, R1 and R2 may be identical or different from each other and each represents a lower alkyl group, and R3 represents a C3-C8 lower alkyl group. a cycloalkyl lower alkyl group or an aryl lower alkyl group. The compound is effective as an elastase inhibitor and a therapeu- tic agent.

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