C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
530/7.1, 195/1.2
C12N 15/09 (2006.01) C07K 1/113 (2006.01) C07K 14/61 (2006.01) C07K 14/81 (2006.01) C07K 19/00 (2006.01) C12N 15/16 (2006.01) C12N 15/62 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1340877
The present invention provides an elastase inhibitory polypeptide comprising a C-terminal half of a human secretory leukocyte protease inhibitor (SLPI) and having an elastase inhibitory activity wherein an inhibitory activity of a trypsin-like serine protease does not excess 1/10 of an elastase inhibitory activity, and polypeptides having the above-mentioned biological activity wherein one or more than one amino acid is added, one or more than one amino acid is deleted and/or one or more than one amino acid is replaced. The present invention also provides a process for the production of the above-mentioned protein or other protein via a corresponding fused protein.
586637
Kamimura Takashi
Masuda Kenichi
Ohtsuka Eiko
Okada Masahiro
Sugiyama Takashi
Mcfadden Fincham
Teijin Limited
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