Elastase treatment of tissue matrices

Details Elastase treatment of tissue matrices Elastase treatment of tissue matrices

A - Human Necessities

61

L

A61L 27/36 (2006.01)

Patent

CA 2726350

A method of produc-ing a modified acellular tissue matrix (mATM) from an acellular tissue ma-trix (ATM), where the mATM has a reduced stretchiness relative to the ATM, without substantially compro-mising its associated structural or functional integrity. The method in-cludes providing an acellular tissue matrix (ATM) and exposing the ATM to elastase for a period of time.

L'invention porte sur un procédé de production d'une matrice de tissu acellulaire modifiée (mATM) à partir d'une matrice de tissu acellulaire (ATM), la mATM ayant une aptitude à l'étirement réduite par rapport à l'ATM, sans compromettre sensiblement son intégrité structurale ou fonctionnelle associée. Le procédé comprend lutilisation d'une matrice de tissu acellulaire (ATM) et l'exposition de l'ATM à une élastase pendant une période de temps.

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