Electrically conductive adhesive hydrogels with solubilizer

Details Electrically conductive adhesive hydrogels with solubilizer Electrically conductive adhesive hydrogels with solubilizer

A - Human Necessities

61

L

A61L 31/14 (2006.01) A61K 47/40 (2006.01)

Patent

CA 2546372

A composition providing electrically conductive adhesive hydrogels suitable for use as skin contact adhesives and, particularly, suitable for use as an electrical interface for disposable medical devices. The present hydrogels provide for reduced skin irritation and/or malodor properties, hydrate a subject's skin, readily wet around a subject's skin surface hair, and protect against burning of a subject upon or due to electrical stimulation through the hydrogel. These hydrogels generally include a monomer, a first initiator, a solubilizer, and a cross-linking agent. The present hydrogels also desirably include a buffer system to help prevent discoloration of the hydrogels and/or hydrolysis of the hydrogels as well as to improve shelf-life. Other additives such as conductivity enhancers, pharmaceuticals, humectants, plasticizers, skin health agents, etc. may be added to the present hydrogels either before or after curing.

L'invention concerne une composition produisant des hydrogels adhésifs électroconducteurs, appropriés à une utilisation comme adhésifs pour contact cutané et, en particulier, comme interface électrique pour dispositifs médicaux jetables. Les présents hydrogels sont moins malodorants et moins irritants pour la peau, hydratent la peau, mouillent facilement les poils à la surface de la peau et protègent contre les brûlures dues à la stimulation électrique par l'intermédiaire de l'hydrogel. Ces hydrogels contiennent généralement un monomère, un premier initiateur, un agent de solubilisation et un agent de réticulation. De préférence, les présents hydrogels contiennent également un système tampon destiné à empêcher la décoloration et/ou l'hydrolyse des hydrogels et à augmenter leur durée de conservation. D'autres additifs, tels que des agents de conductivité, des agents pharmaceutiques, des humectants, des plastifiants, des agents de soin dermatologique, etc. peuvent être ajoutés auxdits hydrogels avant ou après le séchage.

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