Electrically responsive promoter system

Details Electrically responsive promoter system Electrically responsive promoter system

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) A61K 41/00 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C12M 1/42 (2006.01) C12N 15/10 (2006.01) C12N 15/54 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2432310

The present invention provides methods and systems for regulating delivery of therapeutic proteins and nucleic acids. Specifically, this involves using a genetically engineered electrically responsive promoter operably linked to a therapeutic gene sequence, wherein expression of said sequence is controlled by an electrical pulse generator.

L'invention concerne des procédés et des systèmes pour la régulation de la distribution de protéines thérapeutiques et d'acides nucléiques. Spécifiquement, il s'agit d'utiliser un promoteur issu du génie génétique, à réactivité électrique, relié opérationnel à une séquence génique thérapeutique, sachant que l'expression de cette séquence est contrôlée par un générateur d'impulsions électriques.

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