Electrochemical reporter system for detecting analytical...

C - Chemistry – Metallurgy – 12 – Q

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Details

C12Q 1/00 (2006.01) C12Q 1/34 (2006.01) C12Q 1/42 (2006.01) C12Q 1/44 (2006.01) C12Q 1/68 (2006.01) G01N 27/327 (2006.01) G01N 27/403 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2300268

An immunochemical and molecular biologic endpoint reporter system in which reaction products, coupled to electrochemically active molecules susceptible to redox recycling or coupled to enzymes capable of proportional generation of said electrochemically active molecules, are detected and/or quantitated using amperiometry in conjunction with a silicon microship possessing a closely spaced interdigitated array of nobel metal electrodes.

La présente invention concerne un système reporteur agissant au point final d'une réaction en biologie moléculaire et en chimie immunologique, couplé à des molécules électrochimiquement actives susceptibles d'un recyclage redox, ou couplé à des enzymes capables d'engendrer une production proportionnelle de ces molécules détectées et/ou quantifiés par amperiométrie, en association avec une micropuce en silicium possédant des électrodes en métal noble disposées selon un alignement matriciel avec un espacement étroit entre elles.

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