Electrochemical sensor and membrane therefor

Details Electrochemical sensor and membrane therefor Electrochemical sensor and membrane therefor

G - Physics

01

N

18/14, 324/23

G01N 27/40 (2006.01) C12M 1/40 (2006.01) C12Q 1/00 (2006.01) C12Q 1/54 (2006.01)

Patent

CA 1249333

ELECTROCHEMICAL SENSOR AND MEMBRANE THEREFOR Abstract of the Disclosure Polymerizable silicon-containing com- pounds are polymerized or further polymerized in dispersed form to form cured layers or membranes when cured or polymerized in a dispersed layer upon removal of the continuous phase during cur- ing to provide a layer or membrane having unex- pectedly good oxygen and glucose-permeability without allowing the passage of electrode-sensi- tive interferants therethrough. The membranes also are permeable to cholesterol, uric acid, and lower alcohols, such as ethanol. The poly- merizable silicon-containing compounds, after dispersion in a continuous phase, such as by including an emulsifier, can be cured in any known manner during removal of the continuous phase, such as by evaporation of water from a water-continuous phase silicon emulsion or dis- persion. A glucose catalyst layer, such as glu- cose oxidase, can be bonded directly to an elec- trical signal-receiving surface, such as an elec- trode, and the membrane applied over the catalyst to form an electrochemical sensor having new and unexpected accuracy. Whole blood is applied directly onto the membrane, allowing passage of glucose and oxygen to the glucose oxidase layer while preventing passage of substantially all other electrode interferants present in whole blood. The glucose and oxygen interact with the glucose oxidase catalyst to produce hydrogen peroxide which is received immediately by the electrode surface. Since the membrane is whole blood compatible, at the conclusion of the measure- ment, the whole blood on the surface of the membrane may be rinsed or wiped off and the sensor is ready for measurement of another specimen.

507190

Affiliated with

Also associated with

Rating

Electrochemical sensor and membrane therefor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Electrochemical sensor and membrane therefor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Electrochemical sensor and membrane therefor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1331883