Electrochemical system for measuring a biological compound...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/00 (2006.01) G01N 33/487 (2006.01)

Patent

CA 2658906

The system comprises a machine for electronic measurement intended to receive an electrochemical sensor comprising a substrate carrying the current collectors enabling connection of the measurement and reference electrodes to the measuring machine. The measurement electrode is coated with a reagent comprising at least the specific enzyme of the biological compound to analyze in a body fluid. The measuring machine can impose at least two different temperatures to allow separation of the signal from the compound being analyzed from those of the other biological compounds interfering with the signal. Application to the assay of glucose in blood with glucose dehydrogenase as enzyme, without interference with maltose.

Le système comprend un appareil de mesure électronique destiné à recevoir un capteur électrochimique comportant un substrat supportant les collecteurs de courant permettant de relier les électrodes de mesure et de référence à l'appareil de mesure. L'électrode de mesure est revêtue d'un réactif comprenant au moins l'enzyme spécifique du composé biologique à analyser dans un fluide corporel. L'appareil de mesure permet d'imposer au moins deux températures différentes pour permettant de séparer le signal du composé à analyser de ceux d'autres composés biologiques interférant avec le signal. Application au dosage du glucose dans le sang avec la glucose déhydrogénase comme enzyme, sans interférence avec le maltose.

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