Electrochemiluminescent monitoring of compounds

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 15/00 (2006.01) C07H 19/20 (2006.01) C09K 11/06 (2006.01) C12Q 1/34 (2006.01) G01N 33/535 (2006.01)

Patent

CA 2222926

The present invention provides detectable compounds comprising a chemically-transformable first compound covalently linked to an electrochemiluminescent compound. These compounds are useful in processes and kits that monitor the status of the first compound and derive information from the monitoring. The figure shows a proposed ECL mechanism depicting reaction steps associated with the use of TPA as a nonconjugated reductant.

La présente invention concerne des composés détectables comprenant un premier composé chimiquement transformable lié par covalence à un composé électrochimioluminescent. Ces composés conviennent pour des procédés et des trousses servant à la surveillance de l'état du premier composé et à l'extrapolation d'informations à partir de cette surveillance. La figure illustre un mécanisme d'électrochimioluminescence (ECL) proposé représentant les étapes de réaction associées à la tri-n-propylamine (TPA) utilisée comme réducteur non conjugué.

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