Electrokinetic concentration device and methods of use thereof

G - Physics – 01 – N

Patent

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Details

G01N 1/40 (2006.01) B03C 5/02 (2006.01) B81B 1/00 (2006.01) G01N 27/447 (2006.01) H01J 49/04 (2006.01) C40B 60/00 (2006.01)

Patent

CA 2700397

The present invention provides a device and methods of use thereof in concentrating a species of interest and/or controlling liquid flow in a device. The methods, inter-alia, make use of a device comprising a fluidic chip comprising a planar array of channels through which a liquid comprising a species of interest can be made to pass with at least one rigid substrate connected thereto such that at least a portion of a surface of the substrate bounds the channels, and an ion-selective membrane is attached to at least a portion of the surface of the substrate, which bounds said channels, or which bounds a portion of a surface of one of said channels. The device comprises a unit to induce an electric field in the channel and a unit to induce an electrokinetic or pressure driven flow in the channel.

La présente invention concerne un dispositif et des procédés d'utilisation de celui-ci dans la concentration d'une espèce d'intérêt et/ou dans le contrôle d'un flux liquide dans un dispositif. Lesdits procédés utilisent notamment un dispositif doté d'une puce fluidique, qui comprend une matrice planaire de canaux à travers laquelle il est possible de faire passer un liquide comprenant une espèce d'intérêt, au moins un substrat rigide étant raccordé à la matrice, de sorte qu'au moins une partie d'une surface du substrat borde les canaux et qu'une membrane de sélection d'ions soit fixée à au moins une partie de la surface du substrat qui borde lesdits canaux ou qui borde une partie d'une surface de l'un desdits canaux. Le dispositif comprend une unité destinée à induire un champ électrique dans le canal, et une unité destinée à induire un flux électrocinétique ou entraîné par la pression dans le canal.

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