Electrokinetic delivery system and methods therefor

Details Electrokinetic delivery system and methods therefor Electrokinetic delivery system and methods therefor

A - Human Necessities

61

N

A61N 1/30 (2006.01)

Patent

CA 2622818

The electrokinetic medicament delivery system includes at least one applicator having a multiplicity of non-conductive micro-needles carried on a non- conductive surface of the applicator. The opposite surface is formed of electrically conductive material for contact with an active electrode. The applicator includes a matrix containing a medicament or a carrier therefor between the opposite surfaces. When the applicator is applied to the individual's skin with the micro-needles penetrating the skin, an electrical current is completed through the power source, the active electrode, medicament, or electrically conductive carrier therefor, the targeted treatment site, the individual's body, a ground electrode and the power supply, thereby electrokinetically driving the medicament through the non- conductive micro-needles into the targeted treatment site.

L'invention concerne un système d'administration de médicament électrocinétique comprenant au moins un applicateur qui comporte une multiplicité de micro-aiguilles non conductrices lesquelles sont disposées sur une surface de support non conductrice de l'applicateur. La surface opposée est constituée d'un matériau électroconducteur destiné à être en contact avec une électrode active. L'applicateur comprend une matrice contenant un médicament ou un support prévu à cet effet entre deux surfaces opposées. Lorsque l'applicateur est appliqué sur la peau d'un individu de manière que les micro-aiguilles pénètrent dans la peau, un courant électrique circule à partir de la source de courant électrique, à travers l'électrode active, le médicament, ou le support électroconducteur prévu à cet effet, le site de traitement cible, le corps de l'individu, une électrode de masse, et le bloc d'alimentation pour guider le médicament de manière électrocinétique à travers les micro-aiguilles non conductrices vers le site de traitement cible.

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