C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
167/322, 195/40,
C12N 9/00 (2006.01) A61K 33/10 (2006.01) A61K 33/14 (2006.01) C12N 5/00 (2006.01)
Patent
CA 1280082
ABSTRACT Processes and compositions are provided for in vitro use in tissue culture media (preferred), perfusion media, and incubation media. Thus, balanced salt solutions are provided wherein the milliequivalent ratio of sodium cations to chloride anions is normalized and wherein optionally at least one near-equilibrium couple is incorporated (bicarbonate-/carbon dioxide, L-lactate-/pyruvate-, and d-betahydroxybutyrate-/acetoacetate-. Regulation of intracellular and extracellular pH, and normalization of intracellular redox state and phosphorylation state is achievable.
484983
Smart & Biggar
Veech Richard L.
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