C - Chemistry – Metallurgy – 25 – B
Patent
C - Chemistry, Metallurgy
25
B
204/52.3
C25B 3/00 (2006.01) C07J 1/00 (2006.01) C07J 17/00 (2006.01) C07J 21/00 (2006.01) C25B 3/04 (2006.01)
Patent
CA 1055881
Abstract of the Disclosure .DELTA.2,5(10)-steroids, which are intermediates for the preparation of valuable pharmaceutical products, are produced from corresponding .DELTA.1,3,5(10)-steroids by electrolytically reducing the latter in liquid ammonia in a divided cell in the presence of an alkali metal salt of a strong acid having a pK value of less than 5, or an undivided cell in the presence of an alkali metal salt of a weak acid having a pK value from 5 to 32. For example, oestrone methyl ether is electrolyti- cally reduced in ammonia in the presence of lithium perchlorate in a divided cell to produce 3-methoxy-.DELTA.2,5(10)-oestradien-17.beta.- -ol.
204982
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