Electronically-solid-phase assay biomolecules

Details Electronically-solid-phase assay biomolecules Electronically-solid-phase assay biomolecules

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/546 (2006.01) G01N 33/552 (2006.01) G01N 33/569 (2006.01) G01N 15/14 (2006.01)

Patent

CA 2238696

Disclosed are materials and methods for detecting biomolecules in samples employing transponders associated with the bead(s) used as the solid phase in the assay, and information pertinent to the assay is encoded on the transponders memory elements. A dedicated read/write device is used remotely to encode or remotely to read the information. The invention can be used in direct or competitive ELISA-type assays, or in multiplex assays for the simultaneous assay of several analytes, including nucleic acids and protein.

Matériaux et méthodes de détection de biomolécules dans des échantillons au moyen de transpondeurs associés aux perles utilisées comme phase solide dans l'analyse. L'information pertinente à l'analyse est codée dans des unités de mémoire des transpondeurs. Un dispositif spécifique lecture/écriture est utilisé pour coder ou lire l'information à distance. L'invention peut être utilisée pour des analyses de type ELISA, ou pour des analyses multiplex permettant de traiter simultanément plusieurs échantillons, y compris des acides nucléiques et des protéines.

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