C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/21 (2006.01) A61K 39/04 (2006.01) C12N 15/00 (2006.01) C12N 15/74 (2006.01) C12N 15/87 (2006.01)
Patent
CA 2587507
Recombinant Mycobacterium strains with improved vaccinal properties for use as vaccinating agents are provided. The parent strains of the recombinant Mycobacterium strains are selected for their potent immunogenicity. The Mycobacterium strains do not display antibiotic resistance, and do not exhibit horizontal transfer to gram-negative bacteria.
L'invention concerne des souches de Mycobacterium recombinante à propriétés vaccinales améliorées en vue d'une utilisation en tant qu'agent de vaccination. Les souches parentes de celles-ci sont choisies pour leur puissante immunogénicité. Les souches de Mycobacterium ne présentent pas de résistance antibiotique, ni de transfert horizontal vers des bactéries à Gram négatif.
Hone David Michael
Sadoff Jerald C.
Sun Ronggai
Aeras Global Tb Vaccine Foundation
Macrae & Co.
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