Electrospun dextran fibers and devices formed therefrom

Details Electrospun dextran fibers and devices formed therefrom Electrospun dextran fibers and devices formed therefrom

D - Textiles, Paper

01

F

D01F 1/10 (2006.01) A61F 13/02 (2006.01) A61L 15/32 (2006.01) D01D 5/00 (2006.01)

Patent

CA 2721162

The invention generally relates to dextran fibers which are preferably electrospun and devices formed from such fibers. In particular, such devices may include substances of interest (such as therapeutic substances) associated with the electrospun fibers. Upon exposure to a liquid the electrospun fibers dissolve immediately and the substances of interest are released into the liquid. Exemplary devices include bandages formed from electrospun dextran fibers and associated agents that promote hemostasis, such as thrombin and fibrinogen.

L'invention concerne de manière générale des fibres de dextrane qui sont de préférence électrofilées et des dispositifs formés à partir de telles fibres. En particulier, de tels dispositifs peuvent comprendre des substances intéressantes (telles que des substances thérapeutiques) associées aux fibres électrofilées. Lors d'une exposition à un liquide, les fibres électrofilées se dissolvent immédiatement et les substances intéressantes sont libérées dans le liquide. Les dispositifs donnés en exemple comprennent des pansements formés à partir de fibres de dextrane électrofilées et des agents associés qui favorisent l'hémostase, telle que thrombine et fibrinogène.

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