Electrostatic coating

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/28 (2006.01) A61J 3/00 (2006.01) A61K 9/16 (2006.01) A61K 9/48 (2006.01) B05B 5/08 (2006.01) B05D 1/04 (2006.01) B05D 1/06 (2006.01)

Patent

CA 2220485

The invention provides apparatus for electrostatically coating a pharmaceutical tablet core with powdered coating material. The apparatus comprises a first rotary drum (12) on which a core is held in electrical isolation from its surroundings but at a potential difference to earth by an electrode which contacts the core. The core is carried past a coating station B at which particles of powder having an opposite potential difference to earth are held in a tray (18). The surface of the drum is held at the same potential difference to earth as the powder particles. The powder is attracted to the core, and not to the drum, coating the exposed surface of the core. The drum carries the coated core past a fusing station C at which a heater fuses the powder to form a continuous film coating. The core is then turned and transferred onto a second drum (12') where the other surface is coated in the same way.

L'invention concerne un appareil permettant d'appliquer par un procédé électrostatique un revêtement sur un noyau pour former un comprimé pharmaceutique. L'appareil comprend un premier tambour rotatif (12) portant le noyau isolé électriquement de son environnement, mais maintenu à un certain potentiel par rapport à la terre au moyen d'une électrode qui vient en contact avec le noyau. Le noyau est transporté au droit d'un poste d'application du revêtement (B), où les particules de poudre sont maintenues à un potentiel opposé par rapport à la terre, dans un plateau (18). La surface du tambour est maintenue au même potentiel par rapport à la terre que les particules de poudre. La poudre est attirée par le noyau et non pas par le tambour, et elle forme un revêtement sur la surface exposée du noyau. Le tambour transporte le noyau avec son revêtement au droit d'un poste de fusion (C) où un dispositif chauffant fait fondre la poudre pour former un revêtement/film continu. Le noyau est ensuite retourné et transféré vers un second tambour (12') où l'autre surface reçoit un revêtement identique.

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