Element provided with a fibrin layer, preparation and use...

A - Human Necessities – 61 – L

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Details

A61L 27/00 (2006.01) A61L 27/22 (2006.01) A61L 27/34 (2006.01) A61L 27/50 (2006.01) A61L 27/60 (2006.01) B01D 69/10 (2006.01) B01D 71/74 (2006.01)

Patent

CA 2348904

An element provided with a layer based on fibrin- or fibrinogen-containing material, said element comprising (a) a hydrophobic or substantially hydrophobic support, which has a porous part with a thickness of 0.1 to 5 mm, and whose pores, extending across its thickness have a node spacing of 5 to 100 µm, one face of said porous part being treated with a compound based on fibrin and/or a fibrinogen-containing material, and (b) a fibrin-based layer covering said treated surface of the support, characterized in that said fibrin-based layer is substantially uniform and homogeneous on said treated surface, and that the fibrin layer and at least the face of the support in contact with the fibrin layer are substantially free of fibrinogen.

L'invention concerne un élément pourvu d'une couche à base d'un matériau fibrinogène ou contenant de la fibrine, ledit élément comprenant (a) un support hydrophobe ou sensiblement hydrophobe qui possède une épaisseur comprise entre 0,1 et 5 mm et dont les pores (qui le traversent en épaisseur) ont espacement entre les noeuds compris entre 5 et 100 µm, une face de ladite partie poreuse ayant été traitée avec un composé à base d'un matériau fibrinogène ou contenant de la fibrine et (b) une couche à base de fibrine recouvrant ladite surface traitée du support et caractérisée en ce qu'elle est sensiblement uniforme et homogène sur toute la surface traitée et en ce que cette couche à base de fibrine et au moins la face du support en contact avec ladite couche sont sensiblement exemptes de fibrinogène.

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