Elimination of immune responses to viral vectors

Details Elimination of immune responses to viral vectors Elimination of immune responses to viral vectors

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 39/12 (2006.01) A61K 39/39 (2006.01) C07K 14/075 (2006.01) C12N 9/02 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2715484

The present invention relates to the use of immunogenic peptides comprising a T-cell epitope derived from a viral vector antigen and a redox motif such as C- (X)2--[CST] or [CST]-(X)2-C in the pre-vention and/or suppression of im-mune responses to viral vectors and in the manufacture of medicaments therefore.

La présente invention concerne l'utilisation de peptides immunogènes comprenant un épitope de lymphocyte T dérivé d'un antigène de vecteur viral et un motif redox tel que C-(X)2-[CST] ou [CST]-(X)2-C, d'une part pour la prévention et/ou la suppression des réponses immunitaires dirigées contre des vecteurs viraux, et d'autre part pour la fabrication de médicaments à cet effet.

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