Elisa for vegf

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/22 (2006.01) C12N 5/16 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2663012

The vascular endothelial growth factor (VEGF) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions, and other pathologies. Antibody-sandwich ELISA methods and kits for VEGF as an antigen are provided to detect types of VEGF levels in biological samples from animal models and human patients and can be used as a diagnostic/prognostic index.

Selon la présente invention, l'activité du facteur de croissance endothéliale (VEGF) dans la circulation sanguine ou d'autres échantillons biologiques d'un patient peut servir d'indice diagnostique et pronostique pour le cancer, le diabète, les maladies du coeur et d'autres pathologies. Des procédés et des kits Elisa de préparation d'anticorps de type sandwich, qui permettent de rechercher VEGF en tant qu'antigène, ont été mis au point pour détecter des niveaux de VEGF dans des échantillons biologiques provenant de modèles animaux et de patients humains, et peuvent être utilisés comme indice diagnostique ou pronostique.

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