Elisa kit for the rapid determination of n-acetyltransferase...

G - Physics – 01 – N

Patent

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G01N 33/545 (2006.01) C12Q 1/48 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2167330

The invention relates to an enzyme linked immunosorbent assay (ELISA) kit for the rapid determination of N-acetyltransferase (NAT2) phenotype which can be used on a routine basis in a clinical laboratory. The ELISA kit allows physicians to: a) individualize therapy of drugs such as amrinone, procainamide, amonafide, dapsone, isoniazid, trimethoprim-sulphamethoxazole (TMP-SMX) and b) to predict susceptibility to carcinogen induced diseases such as bladder and colon rectal cancers.

'invention a trait à un kit ELISA (méthode immuno-enzymatique) servant à la détermination rapide du phénotype N-acétyl-transférase (NAT2) et utilisable dans les opérations courantes d'un laboratoire clinique. Le kit ELISA permet aux médecins : a) d'individualiser l'utilisation thérapeutique de médicaments tels que : amrinone, procaïnamide, amonafide, dapsone, izoniazide, triméthoprime-sulfaméthoxazole (TMP-SMX) et b) de prévoir la sensibilité à des maladies causées par des carcinogènes, telles que les cancers de la vessie et du colon/rectum.

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