Elongases and processes for the production of...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/82 (2006.01) C12N 9/02 (2006.01)

Patent

CA 2695112

The invention relates to polynucleotides from Pythium irregulare, Rhizobium oryzae and Euglena gracilis which code elongases and which can be used for the recombinant production of polyunsaturated fatty acids. The invention also relates to vectors, host cells and transgenic non-human organisms that contain said inventive polynucleotides, and also the polypeptides coded by said polynucleotides. The invention further relates to anti-bodies against said inventive polypeptides. Finally, the invention relates to production methods for polyunsaturated fatty acids, for oil, lipid and fatty acid compositions and to the use thereof as medicaments, cosmetics, food, animal food in particularly fish food or food supplements.

La présente invention concerne des polynucléotides de Pythium irregulare, Rhizobium oryzae et Euglena gracilis, qui codent des élongases et qui peuvent être utilisés pour produire par recombinaison des acides gras polyinsaturés. L'invention concerne également des vecteurs, des cellules hôtes et des organismes transgéniques non humains qui contiennent lesdits polynucléotides, ainsi que les polypeptides codés par lesdits polynucléotides. Elle concerne aussi des anticorps dirigés contre lesdits polypeptides. En outre, l'invention concerne des procédés de production d'acides gras polyinsaturés, de compositions de graisses, de lipides et d'acides gras, ainsi que leur utilisation comme médicaments, produits cosmétiques, aliments, aliments pour animaux, de préférence aliments pour poissons, ou comme compléments alimentaires.

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