C - Chemistry – Metallurgy – 08 – F
Patent
C - Chemistry, Metallurgy
08
F
C08F 22/32 (2006.01) A61L 24/06 (2006.01) C08F 20/32 (2006.01)
Patent
CA 2452505
Compositions for embolization are disclosed herein. The compositions disclosed can have a matrix-forming component, a solid-aggregate material, and a rheology modifying agent, wherein the matrix-forming component includes at least alkyl cyanoacrylate nomomers, a stabilizer, and a plasticizer, and the solid-aggregate material includes at least a radiopacifier. The composition and a method of administering the composition are useful for treating vasculature abnormalities, particularly when the composition solidifies upon contact with an ionic environment, such as blood.
L'invention concerne des compositions destinées à l'embolisation. Lesdites compositions peuvent contenir un composant formant une matrice, un agrégat solide, et un agent modifiant la rhéologie, le composant formant une matrice comprenant au moins des monomères cyanoacrylates d'alkyle, un stabilisant et un plastifiant, et l'agrégat solide comprenant au moins un opacifiant. Ladite composition et un procédé d'administration de cette dernière sont utiles pour le traitement d'anomalies du système vasculaire, en particulier lorsque la composition se solidifie au contact d'un environnement ionique, tel que le sang.
Boston Scientific Limited
Ridout & Maybee Llp
Scimed Life Systems Inc.
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