Embolus therapy using insoluble microparticles or vesicles...

A - Human Necessities – 61 – K

Patent

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Details

A61K 49/00 (2006.01) A61K 9/14 (2006.01) A61K 9/48 (2006.01) A61K 31/7004 (2006.01) A61K 33/42 (2006.01) A61K 38/00 (2006.01) A61K 38/21 (2006.01) A61K 38/22 (2006.01) A61K 41/00 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61K 49/04 (2006.01) A61K 51/00 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2288292

The invention provides a method of embolus therapy comprising administering into the vasculature of a perfused zone of tissue in a human or non-human animal subject a composition comprising particles of a size or formulation selected to generate emboli at a target site within said subject, characterised in that as said particles are used solid water-insoluble particles of a non-radioactive diagnostically effective compound or vesicles encapsulating a non-radioactive diagnostically effective compound or a solution thereof, and in that embolus location is detected by a diagnostic imaging technique.

L'invention porte sur un procédé de traitement des emboles qui consiste à administrer dans le système vasculaire d'une zone perfusée du tissu d'un animal ou d'un être humain une composition comprenant des particules d'une taille ou d'une formulation sélectionnée de façon à générer des emboles sur un site cible du sujet. Cette invention se caractérise en ce que les particules utilisées sont des particules solides insolubles dans l'eau d'un composé diagnostiquement efficace et non radioactif ou des vésicules renfermant ce type de composé, ou une solution de celles-ci, et en ce que l'emplacement de l'embole est détecté par une technique d'imagerie diagnostique.

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