Embryo modification and implantation

Details Embryo modification and implantation Embryo modification and implantation

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2481256

The present invention relates to constructs and methods used to enhance the attachment and implantation of an embryo. It is shown that modified glycolipids and glycolipid-attachment molecule constructs can be used to modify embryos, or localised to target tissues, to enhance interaction between the embryo and the target tissue, (typically the endometrium). The invention may advantageously be used to enhance implantation of embryos in the uterus, for example, in IVF treatments.

La présente invention concerne des constructions et des procédés servant à améliorer la liaison et l'implantation d'un embryon. Des glycolipides et des constructions de molécules de liaison de glycolipides modifiés peuvent être employés pour modifier des embryons, ou localisés sur des tissus cibles afin d'améliorer l'interaction entre l'embryon et les tissus cibles (en particulier l'endomètre). De manière avantageuse, les procédés selon l'invention peuvent être employés pour améliorer l'implantation dans l'utérus, par exemple dans le cas de traitements de fécondation in vitro.

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