Embryonic-like stem cells derived from post-partum mammalian...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/073 (2010.01) C12N 5/0735 (2010.01) A01N 1/02 (2006.01) A61K 35/50 (2006.01) A61P 9/10 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01) C12N 5/00 (2006.01)

Patent

CA 2476553

The present invention provides compositions and methods of using embryonic- like stem cells that originate from a post-partum placenta with conventional cord blood compositions or other stem or progenitor cells. The embryonic-like stem cells can be used alone or in a mixture with other stem cell populations. In accordance with the present invention, the embryonic-like stem cells may be mixed with other stem cell populations, including but not limited to, umbilical cord blood, fetal and neonatal hematopoietic stem cells and progenitor cells, human stem cells and progenitor cells derived from bone marrow. The embryonic-like stem cells and the mixed populations of embryonic- like stem cells and stem cells have a multitude of uses and applications, including but not limited to, therapeutic uses for transplantation and treatment and prevention of disease, and diagnostic and research uses.

L'invention concerne des compositions et des procédés visant à utiliser des cellules souches de type embryonnaire dérivées de placenta post-partum, en combinaison avec des compositions de sang ombilical classiques ou autres cellules souches ou progénitrices. Les cellules souches de type embryonnaire considérées peuvent être utilisées isolément ou en combinaison avec d'autres populations de cellules souches. Aux fins de l'invention, on peut combiner les cellules souches de type embryonnaire considérées avec d'autres populations de cellules souches, y compris mais pas seulement le sang ombilical, les cellules souches hématopoïétiques foetales et néonatales et les cellules progénitrices, ou les cellules souches et progénitrices humaines dérivées de moelle osseuse. Les cellules souches de type embryonnaire décrites et les populations mixtes de cellules souches de type embryonnaire et de cellules souches ont une multitude d'utilisations et d'applications, y compris mais pas seulement les utilisations thérapeutiques aux fins de transplantation, de traitement et de prévention des maladies, de diagnostic et de recherche.

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