C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/00 (2006.01) C12Q 1/68 (2006.01) C40B 30/00 (2006.01) C40B 40/06 (2006.01)
Patent
CA 2659231
A method of predicting the development of a cancer in a patient, comprises procuring a sample of tumour tissue from the patient, determining the expression pattern of embryonic stem cell genes in the tissue, comparing the expression pattern with the corresponding expression pattern of embryonic stem cell genes in tumour tissue of reference patients with known disease histories. Also disclosed are microarrays and DNA/RNA probes for use in the method.
L'invention concerne un procédé visant à prédire le développement d'un cancer chez un patient. Ce procédé consiste à: fournir un échantillon de tissu tumoral provenant du patient, déterminer le motif d'expression des gènes de cellules souches embryonnaires du tissu, comparer le motif d'expression au motif d'expression correspondant des gènes de cellules souches embryonnaires du tissu tumoral de patients de référence présentant des antécédents pathologiques connus. L'invention concerne également des micro-réseaux et des sondes d'ADN/ARN utilisés dans le procédé de l'invention.
Chundsell Medicals Ab
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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