Embryotoxic factors

Details Embryotoxic factors Embryotoxic factors

C - Chemistry, Metallurgy

12

Q

C12Q 1/04 (2006.01) A61K 31/57 (2006.01) A61K 35/52 (2006.01) A61K 39/00 (2006.01) G01N 33/50 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2163450

Methods and compositions for diagnosing and treating immunologic reproductive failure in a mammal are provided. The methods include determining presence of an elevated concentration of an extracellular embryotoxic factor in a sample. The sample contains leukocytes or leukocyte secretion products. Kits for determining the concentration of embryotoxic factors are also provided.

L'invention concerne des procédés et des compositions de diagnostic et de traitement d'anomalies reproductives immunologiques chez le mammifère. Lesdits procédés consistent à déterminer la présence d'une concentration élevée d'un facteur embryotoxique extracellulaire dans un échantillon. Ledit échantillon contient des leucocytes ou des produits de sécrétion de leucocytes. L'invention porte également sur le matériel permettant de déterminer la concentration desdits facteurs embryotoxiques.

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