Emulsion compositions for the parenteral and/or oral...

A - Human Necessities – 61 – K

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167/159, 167/163

A61K 9/10 (2006.01) A61K 9/107 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/44 (2006.01)

Patent

CA 1272447

TITLE: EMULSION COMPOSITIONS FOR THE PARENTERAL AND/OR ORAL ADMINISTRATION OF SPARINGLY WATER SOLUBLE IONIZABLE HYDROPHOBIC DRUGS ABSTRACT OF THE DISCLOSURE This disclosure describes quick breaking, in vivo, intravenous, intramuscular, intraarticular and/or oral fat emulsion compositions which incorporate the use of benzyl alcohol as a cosurfactant and/or a cosolvent in combination with materials such as synthetic surfactants, e.g. sorbitan triisostearate, triglycerol diisostearate or triglycerol pentaoleate; naturally occurring vegetable oils, e.g. sesame oil, and soybean oil; natural lecithins such as egg lecithin or soy lecithin; saturated or unsat- urated aliphatic acids, e.g. oleic acid, hexanoic acid and linolenic acid; and other excipients such as glycerine, polyvinylpyrrolidone, Pluronic? F-68 and dl-.alpha.-tocopherol.

518052

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