Emulsion particles for imaging and therapy and methods of...

Details Emulsion particles for imaging and therapy and methods of... Emulsion particles for imaging and therapy and methods of...

A - Human Necessities

61

K

A61K 51/00 (2006.01) A61B 5/055 (2006.01)

Patent

CA 2534426

Emulsions preferably of nanoparticles formed from oil compounds coupled to a high Z number atom, said particles coated with a lipid/surfactant coating. The nanoparticles are made specific to targeted cells or tissues by coupling said nanoparticles to a ligand specific for the target cells or tissues. The nanoparticles may further include biologically active agents, radionuclides and/or other imaging agents.

L'invention concerne des émulsions contenant de préférence des nanoparticules formées à partir de composés d'huile couplés à un atome de nombre Z élevé, lesdites particules étant revêtues par un revêtement lipide/tensioactif. Lesdites nanoparticules sont rendues spécifiques de cellules ou de tissus ciblés par couplage de celles-ci à un ligand spécifique des cellules ou tissus cibles. Lesdites nanoparticules peuvent en outre comprendre des agents actifs sur le plan biologique, des radionucléides et/ou d'autres agents d'imagerie.

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