Emulsions as solid dosage forms for oral administration

Details Emulsions as solid dosage forms for oral administration Emulsions as solid dosage forms for oral administration

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01)

Patent

CA 2437762

Novel emulsion compositions which improve the rate and/or extent of absorption of drugs are disclosed. The novel emulsion compositions of the present invention include drug-containing emulsions adsorbed onto solid particles which may be further formulated into solid dosage forms, methods of preparing such emulsion compositions and their uses thereof. The emulsion compositions and their dosage forms improve the drug-load and the bioavailability of a wide range of drugs including drugs that are known or suspected of having poor bioavailability by the utilization of several different mechanisms.

La présente invention concerne de nouvelles compositions d'émulsion qui améliorent le taux et/ou l'ampleur d'absorption de médicaments. Les nouvelles compositions d'émulsion de la présente invention comprennent des émulsions renfermant des médicaments adsorbés sur des particules solides qui peuvent être davantage formulés sous formes posologiques solides, des procédés de préparation de telles compositions d'émulsion et leurs utilisations. Les compositions d'émulsion et leurs formes posologiques améliorent la charge de médicaments et la biodisponibilité d'une large gamme de médicaments connus pour ou susceptibles de présenter une faible biodisponibilité par l'utilisation de plusieurs mécanismes différents.

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