Emulsions of a protein-crosslinked hydrogel matrix and...

Details Emulsions of a protein-crosslinked hydrogel matrix and... Emulsions of a protein-crosslinked hydrogel matrix and...

A - Human Necessities

61

K

A61K 9/107 (2006.01) A61L 15/32 (2006.01) A61L 15/34 (2006.01) A61L 15/44 (2006.01)

Patent

CA 2631497

Disclosed are oil-in- water emulsion gels comprising a hydrogel matrix, a gel- forming hydrophilic polymer covalently crosslinking a protein, with a hydrophobic phase dispersed therein. The hydrophobic phase optionally contains a biologically active agent, and is preferably an omega-3 oil. The gels can be used as drug delivery devices or preferably wound dressings Also disclosed are methods for making said emulsion gels

La présente invention concerne des gels en émulsion huile dans l'eau qui comprennent une matrice d'hydrogel, un polymère hydrophile formant un gel réticulé de façon covalente avec une protéine, et contenant une phase hydrophobe dispersée à l'intérieur de celui-ci. La phase hydrophobe contient éventuellement un principe actif biologique, et est préférentiellement une huile oméga-3. Les gels peuvent être employés en tant que dispositifs de libération de médicaments ou, de façon préférentielle, en tant que bandages. La présente invention concerne également des méthodes de fabrication desdits gels en émulsion.

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