Emulsions of perfluorocarbons

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 23/00 (2006.01) A01N 1/02 (2006.01) A61K 8/70 (2006.01) A61K 9/107 (2006.01) A61K 47/06 (2006.01) A61P 7/00 (2006.01) A61P 17/02 (2006.01) A61P 39/04 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2756685

The subject application provides for an emulsion comprising an amount of a perfluorocarbon liquid dispersed as particles within a continuous liquid phase, wherein the dispersed particles have a monomodal particle size distribution and uses thereof. The subject application also provides for a method of manufacturing a perfluorocarbon emulsion, a process for preparing a pharmaceutical product containing a PFC emulsion and a process for validating a batch of an emulsion for pharmaceutical use.

La présente invention concerne une émulsion comprenant une quantité de liquide de perfluorocarbone dispersée en tant que particules dans une phase liquide continue, les particules dispersées présentant une répartition de taille de particule monomodale. L'invention porte également sur des utilisations de celle-ci. La présente invention concerne en outre un procédé de fabrication d'une émulsion de perfluorocarbone, un procédé de préparation de produit pharmaceutique contenant une émulsion de PFC, et un procédé de validation d'un lot d'une émulsion pour un usage pharmaceutique.

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