C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/00 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2469089
The present invention relates to a method for determining a predisposition to develop cancer in a patient, comprising the step of detecting EN 2 gene or its expression product in said patient or in a biological sample of said patient, whereby detecting presence of at least one of EN 2 gene or its expression product is indicative of a predisposition to develop breast cancer. The present invention also relates to antisense hybridizine to EN2 gene kits for determining predisposition to develop cancer and method of reducing EN2 expression.
Martin Nicole
Meloche Sylvain
Saba El-Leil Marc
Sauvageau Guy
Institut de Recherches Cliniques de Montreal
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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