C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61L 27/00 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2226570
The invention relates to novel nucleic acid fragments encoding polypeptides which are capable of mediating contact between enamel and cell surface. The invention also relates to expression vectors containing the nucleic acid fragments according to the invention for production of the protein, organisms containing said expression vector, methods for producing the polypeptide, compositions comprising the polypeptides, antibodies or antibody fragments recognizing the polypeptides, and methods for treating various hard tissue diseases or disorders.
L'invention concerne des nouveaux fragments d'acide nucléique codant des polypeptides qui peuvent induire un contact entre l'émail et la surface cellulaire. L'invention concerne également des vecteurs d'expression contenant les fragments d'acide nucléique selon l'invention, aux fins de production de la protéine, des organismes contenant ce vecteur d'expression, des procédés de production du polypeptide, des compositions comprenant ces polypeptides, des anticorps ou des fragments d'anticorps reconnaissant les polypeptides, ainsi que des procédés de traitement de divers troubles ou affections concernant les tissus durs.
Cerny Radim
Fong Cheng Dan
Hammarstrom Lars
Slaby Ivan
Wurtz Tilmann
Biora Ab
Sim & Mcburney
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