C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/54 (2006.01) A61K 31/343 (2006.01) A61P 9/06 (2006.01)
Patent
CA 2392016
The subject invention pertains to novel enantiomerically pure compounds, and compositions comprising the compounds, for the treatment of cardiac arrhythmias. The subject invention further concerns a method of making and purifying the compounds. The enantiomerically purified compounds, and compositions of these compounds, exhibit unexpectedly distinct and advantageous characteristics, such as a markedly superior ability to reduce or inhibit ventricular premature beats, as compared to racemic mixtures of the compounds.
La présente invention de rapporte à de nouveaux composés énantiomériquement purs et à des compositions contenant ces composés et destinées au traitement des arythmies cardiaques. Elle se rapporte en outre à un procédé de fabrication et de purification de ces composés. Ces composés énantiomériquement purifiés et les compositions contenant ces composés possèdent des caractéristiques avantageuses et distinctes non prévisibles, telles qu'une capacité à réduire ou inhiber les extrasystoles ventriculaires nettement supérieure à celle des mélanges racémiques de ces composés.
Druzgala Pascal
Milner Peter G.
Aryx Therapeutics
Aryx Therapeutics Inc.
Mbm Intellectual Property Law Llp
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